BioBricks and Standardized Genetic Parts (Microbes as Machines)

[[Media:Spring2015_BioBricks_Pre-Discussion_Questions.pdf| Download Pre-Discussion Questions (PDF)]]
[T]he engineering of biology remains complex because we have never made it simple. --attributed to Tom Knight

= Required Reading =

// Classic paper first describing BioBricks. // Describes how synthetic biology perspective differs from "mere" recombinant DNA technology and metabolic engineering. Introduces key concepts such as standardization, decoupling, abstraction, // Overview of the iGEM competition.
 * 1) Knight2003 Knight T Idempotent Vector Design for Standard Assembly of Biobricks 2005 http://dspace.mit.edu/handle/1721.1/21168
 * 1) Endy2005 pmid=16306983
 * 1) Vilanova2014 pmid=24811510

= Assigned Papers =
 * 1) Anderson2010 pmid=20205762
 * 2) Alnahhas2014 pmid=25525459

= Supplementary Information =


 * Movie of restriction enzyme EcoR1
 * Presentation describing BioBrick Standard Assembly (J. Christopher Anderson)