Biocontainment (Microbes as Machines)

[[Media:Spring2015_Biocontainment_Pre-Discussion_Questions.pdf|Download Pre-Discussion Questions (PDF)]]
...if speculations correctly predict the future use of synthetic biology, the technology will scale to large industrial volumes, introduce large numbers of synthetic organisms into the environment for bioremediation, and be used in private spaces where dispersal and disposal are difficult to monitor Moe-Behrens2013.

= Required Reading/Viewing =

// Reviews the development of biocontainment technologies for organisms and recombinant genes
 * 1) Moe-Behrens2013 pmid=23355834

= Assigned Papers =

// Using a nonnatural base in DNA replicated in a living organism // Creation of a plasmid that prevents recombinant genes from being transferred to other organisms // Tests of multiple biocontainment strategies for organisms
 * 1) Malyshev2014 pmid=24805238
 * 1) Wright2015 pmid=24847673
 * 1) Gallagher2015 pmid=25567985