DNA for Information Storage (Microbes as Machines)

[[Media:Spring2015_DNA_for_Information_Storage_Pre-Discussion.pdf|Download Pre-Discussion Questions (PDF)]]
...DNA storage is very dense. At theoretical maximum, DNA can encode two bits per nucleotide (nt) or 455 exabytes per gram of single-stranded DNA. Church2012

= Required Reading/Viewing =

// George Church encodes his book in DNA. See the [supplement] for lists of previous biological information storage. // Commentary on above paper. // Most copies of an album ever sold in a few drops of liquid?
 * 1) Church2012 pmid=22903519
 * 1) Sennels2012 pmid=23104084
 * 1) Marantz2014 Marantz, A. Petri-Dish Pop The New Yorker Nov. 24, 2014.

= Assigned Papers =

// More detailed treatment of costs/benefits of DNA storage by EBI and CERN teams. Commentary article by Ed Yong: Shakespeare’s Sonnets and MLK’s Speech Stored in DNA Speck // Addition of storage in silica to stabilize DNA. Press release by ETH Zurich: Data-storage for eternity
 * 1) Goldman2013 pmid=23354052
 * 1) Grass2015 pmid=25650567